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Intracytoplasmic Sperm Injection (ICSI)

Intracytoplasmic sperm injection (ICSI) is a precise lab procedure used in assisted reproduction. It is particularly helpful when male infertility is severe, such as very low sperm count, poor motility, or abnormal sperm shape.

ICSI involves injecting a single sperm directly into a mature egg under a microscope. This bypasses natural barriers that may prevent fertilization. The eggs are retrieved from the woman following ovarian stimulation, similar to IVF. Sperm is collected from the partner or a donor. If needed, surgical methods like TESA or PESA can retrieve sperm directly from the testicles.

After injection, eggs are monitored for fertilization and embryo development. Healthy embryos are then cultured and assessed for quality. The best embryos are transferred into the uterus at the right stage. Hormonal support may be provided to aid implantation.

ICSI has improved fertilization rates for couples facing male factor infertility. It also helps those who have had failed IVF cycles in the past. While it is more advanced than conventional IVF, it remains safe when performed in a certified laboratory.

The procedure allows couples with significant sperm issues to have a realistic chance of conception. It’s an important option when other methods are unlikely to succeed.